There are a few basic health matters that require care and attention.
For southern Africa (Botswana, Namibia, South Africa, Malawi, Mozambique, Zambia and Zimbabwe) there are no required inoculations and health concerns are the same as those for travel to some parts of South East Asia, Eastern Europe or the Caribbean.
For East Africa (Kenya, Tanzania, Rwanda and Uganda) and Central Africa (the Republic of Congo) health concerns and inoculations are the same as those for travel to the Indian subcontinent, Indochina or South America.
No matter where you travel in Africa (except in malaria-free areas in South Africa and Kenya) a course of anti-malaria tablets is recommended.
There are no other health issues that one needs to be overly concerned with. We strongly recommend that you visit your local travel health specialist in your home country for further professional advice.
The vast majority of travellers to Africa return from their safaris healthier (in mind and in body) than when they went.